Black spot inside the cheek: is it serious?

Black spots inside the cheek can have several causes, such as blisters or hyperpigmentation. In rare cases, they may indicate something more serious, such as oral cancer. Many benign conditions can cause a black spot to appear on the inside of the cheek. Often there will be no other symptoms, and the condition will get better without treatment. In rare cases, however, a black spot on the inside of the cheek can be a symptom of oral melanoma. It is a rare type of cancer.

Here are some potential causes of a black spot inside the cheek. As well as some treatment options and when a person should contact their doctor.

Main causes of black spots inside the cheek

– Blisters of blood

Blisters are raised bubbles on the skin with fluid inside. They can occur anywhere on the body, including in the mouth. Blood blisters contain blood and appear dark red or purple. They can develop in the mouth as a result of an accidental biting of the cheek or an allergic reaction.


Blood blisters are usually not harmful, and they often heal without treatment. Sometimes, however, they can cause pain or discomfort. In these cases, over-the-counter pain medications can be used.

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– Amalgam tattoos

Amalgam tattoos occur when metal fillings leak, causing dark marks to appear inside the mouth. These marks can appear when a dentist places or removes a filling and tiny fragments of metal fall between the teeth. They most often appear on the gum or the cheek, near the filling. However, they can appear anywhere in the mouth.


Amalgam tattoos cause no symptoms and do not require any form of treatment.

– Smoking

Smoking can cause smoker’s melanosis. This is a condition in which brown or black pigmentation develops inside the mouth and throat.


This condition is not harmful and does not require treatment. However, the tobacco smoke that causes these spots is harmful to various areas of the body. For example, smoking can cause gum disease, tooth loss, and oral cancer, along with several other conditions.

– Oral melanoma

Melanoma is a cancer of the pigment-producing cells, or melanocytes, which usually affects the skin. However, these cancers can also occur on mucous membranes, such as in the mouth. Oral melanoma usually appears as a raised area that looks black, brown, or dark blue. These marks may be asymmetrical with an uneven edge. There may also be swelling, if inflamed.

Researchers don’t know exactly what the risk factors are, but they may include:

dental irritation
Alcohol consumption


The main treatment option for oral melanoma is surgery. Your doctor may also recommend radiation therapy.

– Addison’s disease

Addison’s disease is an endocrine disorder that occurs when the adrenal glands, which are the glands at the top of the kidneys, do not make enough of certain hormones. These include cortisol and aldosterone. Addison’s disease can cause darker areas to develop on the skin and inside the mouth.

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Other symptoms can be observed:

chronic fatigue
muscular weakness
abdominal pain
loss of appetite


Treatment for Addison’s disease will include hormone replacement medications. People can take a corticosteroid, such as hydrocortisone, to replace missing cortisol.

How to diagnose the origin of a black spot inside the cheek

A doctor or dentist will perform a physical examination of the blackheads to determine the cause. He will likely ask the person if the spots are painful or come with symptoms. A doctor may also check a person’s medical history for any signs of a genetic condition, such as Peutz-Jeghers syndrome, that may be the cause. He may also examine the person’s dental records for the presence of metal fillings. Based on their evaluation, your doctor may also order additional tests to make a definitive diagnosis. For example, he may require a blood test or a skin sample for further analysis.

When to contact a doctor for a black spot inside the cheek

Many causes of dark spots inside the cheek, such as amalgam tattoos, are harmless. Although no medical treatment is needed for some causes of black cheek patches, one should contact a doctor for any sore or spot that lasts longer than three weeks. If the black areas develop sores or ulcers, these may be symptoms of oral cancer. Early detection of oral cancer is crucial for successful treatment.

Do not panic in case of black spot inside the cheek

The possible causes of black spots inside the cheek are many. For most people, these spots cause no additional symptoms and do not require treatment. Some people may need over-the-counter treatments for causes that cause pain, such as blood blisters. Other causes, such as oral cancer, will require medical treatment. Although black spots inside the mouth can be harmless, it is worth seeing a doctor for persistent cases. They can help determine if the stain is harmless or if it requires additional care.

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Adrenal insufficiency & Addison’s disease. (nd).

Ahmadi-Motamayel, F., et al. (2013). Report of a rare and aggressive case of oral malignant melanoma.

Canker sores (mouth ulcers): Overview. (2019).

Kanagaraj, S., et al. (2018). A short review on smoker’s melanosis.

Key statistics for oral cavity and oropharyngeal cancers. (2021).

Mouth cancer. (2020).

Mouth sores and pain. (2020).

Mouth ulcers. (nd).

Ni Riordain, R. (2014). Amalgam tattoo.

* The information and services available on pressesante.com in no way replace the consultation of competent health professionals. [HighProtein-Foods.com]

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