A diet rich in tomatoes and by-products, as found in a Mediterranean-type diet, in postmenopausal women at high risk of breast cancer, would lead to certain favorable hormonal changes, which has not been observed with a diet rich in soy, according to a study published in the Journal of Clinical Endocrinology & Metabolism.
The risk of breast cancer after menopause increases all the more as weight gain is significant. In this new study conducted by Rutgers University, the authors wanted to assess the impact of a diet rich in carotenoids, in particular lycopene from tomatoes, and a diet rich in isoflavones from soybeans, on serum levels. of adiponectin. This hormone acts positively on certain metabolic risk factors associated with excess weight, among other things by promoting insulin sensitivity.
Women better protected with lycopene from tomatoes
The study was conducted among 70 postmenopausal women with a high risk of breast cancer, according to a cross-over protocol: a period of 10 days with daily at least 25 mg of lycopene through tomatoes and derivatives, and , at 2-week intervals, a 10-day period during which the women ingested 40 grams of soy protein daily. With the tomato period, rates rose by 9%. The effect was more marked in women who were not obese. Conversely, the soy period resulted in a reduction in adiponectin levels.
The authors conclude that the consumption of tomatoes and derivatives can favorably influence the level of adiponectin in postmenopausal women at high risk of breast cancer, especially in those who are not obese. However, other studies are needed to clarify the preventive potential of a diet rich in lycopene.
Lianos A. et al. Journal of Clinical Endocrinology & Metabolism.