A study conducted in postmenopausal women reports that calcium and vitamin D supplementation is not only beneficial for bones, but also for blood lipids, especially cholesterol.
The calcium and vitamin D tandem is well known for its favorable effects on bone health. In a study of 600 postmenopausal women, a team from The Reading Hospital and Medical Center in the United States looked at the effects of calcium and vitamin D supplementation on blood lipids.
The study, conducted double-blind, compared the administration of 1000 mg of calcium and 10 mcg (400 IU) of vitamin D with that of a placebo. The intervention was spread over two years.
Better vitamin D levels and lower cholesterol
Unsurprisingly, the results reveal, in women taking the supplement, an increase in blood concentrations of 25OHD3 (+38% on average). Women in the supplemented group were twice as likely to achieve desired vitamin D levels of min. 30 ng/ml, compared to those in the placebo group.
But above all, the authors noted a modest but significant reduction in LDL cholesterol levels (-4.46 mg/dl on average). Their analyzes also indicate that a high concentration of 25OHD3 is associated with higher HDL cholesterol levels, and lower LDL and triglyceride levels.
These results are all the more interesting when we know that from the menopause, the disappearance of estrogens leads to a modification of the lipid profile, with in particular a reduction in HDL.
Schnatz PF et al: Women’s Health Initiative clinical trials: potential interactive effect of calcium and vitamin D supplementation with hormonal therapy on cardiovascular disease. Menopause. doi: 10.1097/GME.0000000000001360.