Cirrhosis Nash-soda-disease- Presse santé

Relatively little known to doctors and patients, Nash cirrhosis (“Non Alcoholic Steato Hepatitis”), English acronym for non-alcoholic hepatic steatosis, or in French non-alcoholic cirrhosis, worries the medical world by its significant expansion. This pathology, nicknamed “soda disease” or “human fatty liver”, concerns between 25 and 30% of the population.

Six million French people would be affected, or 12% of the population, by “the soda disease”. By 2020, this disease could become the first cause of liver transplants, ahead of hepatitis C. Caused by an overload of the liver with fat, this pathology is mainly caused by excessive consumption of sugary drinks, fats or sugars. . Ducks force-fed to obtain foie gras are also affected. The liver which receives an overload of fat then no longer manages, after a few years, to eliminate it. The organ then stores fatty acids, causing inflammation that can lead to fibrosis (formation of scar tissue) that can progress to cirrhosis or even cancer. Including in patients who do not drink alcohol.

Regularly drinking sugary drinks increases the risk by 55%

According to a study published in the “Journal of Hepatology” in August 2015, conducted on 2,634 patients, people who drink sugary drinks daily have a 55% increased risk of developing metabolic steatosis.

On the other hand, in view of this study, the consumption of so-called “light” drinks is not associated with an increased risk of developing “fatty liver disease”. Even though artificial sweeteners have long been suspected by scientists to cause the same mechanisms as “real” sugars, namely triggering an insulin spike that promotes fat accumulation. 5% of patients will eventually develop liver cancer and 20% of deaths caused by the disease are due to cardiovascular complications.

90% of overweight people affected

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The increase in the number of cases of non-alcoholic cirrhosis or “fatty liver disease” is closely linked to the epidemic of diabetes and obesity in developed countries, people with it are indeed particularly at risk. . Thus, 22% of diabetics would be affected and 90% of obese people would be affected.


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