Irritable bowel syndrome: aluminum pointed out

This is a new track that is emerging for irritable bowel syndrome, which could find its genesis in part in too high exposure to aluminum.

The origin of irritable bowel syndrome remains largely unknown and, so far, research has focused on factors that could alter the balance of the intestinal microbiota. Aluminum is now added to the list of these many factors.

Aluminum accumulates in the intestines and disrupts everything

38% of ingested aluminum accumulates in the intestinal mucosa, which, according to the researchers, seems deleterious for the homeostasis of the intestine. Ingested aluminum thus affects the regulation of gut permeability, microflora, and immune function, and many arguments support considering aluminum as an environmental risk factor for inflammatory bowel disease. , write the researchers in Morphologie.

Aluminum absorbed through food

Diet is the main source of aluminum exposure:

– by its natural presence: it is the most abundant metal in the earth’s crust,

– but also by the use of food additives containing this element.

Food absorption takes place mainly through by-products (bread, cakes, biscuits and pastries), vegetables (mushrooms, spinach, radish and lettuce), beverages (tea and cocoa), drinking water constituting only a minor source.

Routes of exposure still include aluminum cooking utensils (including aluminum foil), certain drugs, and airborne dust.


Vignal C. et al. Gut: An underestimated target organ for Aluminum, Morphologie, doi.org/10.1016/j.morpho


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