Ketogenic diet: choosing the right source of your proteins

A new study shows that when the diet is low in carbohydrates, as in the context of a ketogenic diet, the benefit of such a diet may cancel out with regard to the occurrence of mortality linked to the origin of lipids and proteins. The benefit is clear in favor of a supply of lipids and proteins of plant origin.

Influence of the origin of proteins and lipids

The popularity of the ketogenic diet, low in carbohydrates, does not weaken, and for good reason, potential positive effects on weight loss, cardio-metabolic risks, migraines, neuro-degenerative diseases and cancer in the short term. assigned. However, the data relating to their impact on long-term health are still poorly understood.

This large study published in the Lancet Public Health journal evaluated the association between carbohydrate consumption and mortality. The researchers analyzed the carbohydrate intake of 15,428 Americans aged 45 to 64 and enrolled in the ARIC (Atherosclerosis Risk in Communities) study, and cross-checked them with total mortality. They then compared this data with that of another large study: PURE.

The researchers examined whether the origin of proteins and fats consumed instead of carbohydrates has an impact on mortality. They observed that:

– A low-carbohydrate diet in which carbohydrates are substituted by proteins and lipids of animal origin is associated with a higher risk of mortality.

– On the contrary, when carbohydrates are replaced by proteins and lipids from vegetable sources, this association is reversed.

This study therefore underlines the importance of focusing mainly on vegetable sources of proteins and lipids in the event of a ketogenic diet in order to reduce the risk of mortality.


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Seidelmann S. et al., Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. The Lancet Public Health, 2018; 3: e419–28.


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