Rheumatism affects 1 in 4 adults and is the leading cause of disability after 40 years. However, a natural compound found in green tea, epigallocatechin-3-gallate (EGCG), is able to block inflammation and tissue destruction in rheumatoid arthritis (RA).
Green tea has been recognized as effective in the prevention of diabetes and obesity, the prevention of certain cancers, of the mouth or colorectal cancer, its stimulating effect of anticancer drugs, via its compound epigallocatechin-3-O -gallate (EGCG), its protective role against cognitive decline and Alzheimer’s, and even against the transmission of HIV.
The effectiveness of green tea against joint pain and inflammation
This natural benefit comes at a time when existing drugs to treat rheumatoid arthritis are expensive and their long-term use is not always appropriate. Here, one of its compounds, epigallocatechin-3-gallate, with already known anti-inflammatory properties, shows promising and targeted potential against rheumatoid arthritis.
Specifically, EGCG targets a key signaling protein, TAK1, used by pro-inflammatory cytokines to transmit their signals responsible for inflammation and tissue destruction. Taking EGCG for 10 days reduces ankle swelling.
Rheumatoid arthritis, ankylosing spondylitis, arthritis, fibromyalgia, gout, lupus,… Rheumatic diseases affect the quality of life of millions of people in more than 200 forms. These diseases affect the joints, bones, cartilage, tendons, ligaments and/or muscles. Silencing them and protecting yourself with cups of green tea is a good idea.
Anil K. Singh et al. Regulation of Transforming Growth Factor β–Activated Kinase Activation by Epigallocatechin‐3‐Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K63‐Linked Autoubiquitination of Tumor Necrosis Factor Receptor–Associated Factor 6. Arthritis & Rheumatology